My interests involve analyzing mathematical and computational models in biochemistry, by using dynamical systems, numerical analysis and scientific computing. Particular topics are parameter-independent dynamical properties of biochemical reaction networks, identifiability of biochemical networks from experimental data, global stability in biochemical network models. I am a co-author of the papers below.

Gheorghe Craciun, Fedor Nazarov, Casian Pantea,
Proof of the persistence conjecture for two-species biochemical reaction networks, in preparation.

Gheorghe Craciun, Casian Pantea,
Persistence and global stability for biochemical reaction network models, in preparation.

Casian Pantea, James B. Rawlings, Gheorghe Craciun,
Solvability of QSSA in chemical kinetics, submitted.

Casian Pantea, Gheorghe Craciun,
Computational methods for analyzing bistability in biochemical reaction networks, submitted.

Gheorghe Craciun, Casian Pantea and Grzegorz A. Rempala,
Dimension reduction for inferring biochemical networks, submitted, available at arXiv:0902.4417v1.

Gheorghe Craciun, Casian Pantea and Grzegorz A. Rempala,
Algebraic methods for inferring biochemical networks: a maximum likelihood approach, Computational Biology and Chemistry, 33, 2009.

Gheorghe Craciun, Casian Pantea,
Identifiability of Chemical Reaction Network, Journal of Mathematical Chemistry, 44:1, 2008.

I have been a Teaching Assistant for the following undergraduate courses at University of Wisconsin-Madison:

Math 222 -- Calculus and Analytic Geometry (Fall 04).

Math 234 -- Calculus -- Functions of Several Variables (Spring 05, Fall 06).

Math 210 -- Topics in Finite Mathematics (Fall 05, Spring 06).

Math 217 -- Calculus with Algebra and Trigonometry II (Fall 07).

I wrote Matlab code that performs various tasks involving kinetics of biochemical reaction networks. A very powerful computer program that deals with mass-action kinetics is Martin Feinberg's Chemical Reaction Network Toolbox. Most of the code below could be made a lot cleaner (I will do that eventially), but it works well and might be useful to other people.

The Network Reader reader.zip reads mass-action reactions and rate constants from a friendly formatted text file, then outputs and plots the concentrations of the chemical species as functions of time.

The BioNetX software BioNetX.zip tests the capacity for multistability of a biochemical system. In its current form, it implements the results of Gheorghe Craciun and Martin Feinberg's paper
Multiple Equilibria in Complex Chemical Reaction Networks: I. The Injectivity Property,
SIAM Journal on Applied Mathematics 65:5, 2005. This code is under development; I am working on incorporating other methods for testing bistability. A beta version of the code that uses free software packages (Maxima and Octave) is available. Please email me if you would like to try it.

The BioNetID code BioNetID.zip uses the Maximum Likelihood Approach introduced in the paper
Gheorghe Craciun, Casian Pantea and Grzegorz A. Rempala,
Algebraic Methods for Inferring Biochemical Networks: a Maximum Likelihood Approach to infer reaction networks from experimental concentration data.

A poster version of the paper on Identifiability of Reaction Networks.

A link to Martin Feinberg's Lectures on Chemical Reaction Networks.

Mathematical/Computational Biology places: MBI  IMA  SAMSI  BACTER.

My better half Sorana is an actuary. She deals with mathematical models for insurance.

I am a member of the Madison student organization From Romania. We have biweekly meetings at the Memorial Union. Please let me know if you would like to join us or to be on our email list.

Sibiu, Romania is number eight in the Forbes list of Europe's Most Idyllic Places To Live.